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National Cancer Institute Fact Sheet
    Reviewed: 07/06/2009
The U.S. National Cancer Institute
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Key Points
  • The U.S. National Cancer Institute (NCI) is part of the National Institutes of Health and the U.S. Department of Health and Human Services (see Question 1).
  • NCI was established by Congress in 1937 (see Question 2).
  • NCI's main responsibilities include coordinating the National Cancer Program; conducting and supporting cancer-related research; training physicians and scientists; and disseminating state-of-the-art information about cancer detection, diagnosis, treatment, prevention, control, palliative care, and survivorship (see Question 3).
  • Most of NCI's budget is used to fund grants and contracts to universities, medical schools, cancer centers, research laboratories, and private firms in the United States and about 60 other countries around the world (see Question 5).
  1. What is the U.S. National Cancer Institute (NCI)?
  2. NCI is 1of 27 Institutes and Centers that comprise the U.S. National Institutes of Health, which is part of the U.S. Department of Health and Human Services.

  3. When was NCI established?
  4. NCI was established by Congress in the National Cancer Institute Act of 1937 1.

  5. What are NCI's main responsibilities and activities?
  6. NCI’s initial responsibilities, as defined in the National Cancer Institute Act, included conducting and fostering cancer research; reviewing and approving grant-in-aid applications to support promising research projects on the causes, diagnosis, treatment, and prevention of cancer; collecting, analyzing, and disseminating the results of cancer research conducted in the United States and in other countries; and providing training and instruction in cancer diagnosis and treatment.

    NCI's responsibilities were later expanded and strengthened in the National Cancer Act of 1971 2. In this legislation, Congress created the National Cancer Program and charged NCI with its coordination.

    In fulfilling its responsibilities, NCI has built a national network that includes regional and community cancer centers, physicians who are cancer specialists, cooperative groups of clinical researchers, and volunteer and community outreach groups.

    In addition, NCI has developed an infrastructure for discovery that consists of support mechanisms, organizations, and networks that link scientists, facilities, resources, and information. This infrastructure provides the foundation for basic, translational, and clinical research activities encompassing all aspects of cancer, including biology, genetics, epidemiology, detection, diagnosis, treatment, prevention, palliative care, and survivorship. NCI’s infrastructure also supports training programs to ensure the continuous development of highly skilled researchers in basic, clinical, cancer control, behavioral, and population sciences. Each year the efforts of thousands of researchers supported by this infrastructure produce scientific advances in all areas of cancer research. Furthermore, NCI has initiated cancer control programs to hasten the application of knowledge gained through research.

    The National Cancer Act of 1971 also expanded the scope of NCI’s international activities to include support of cancer research outside the United States by highly qualified foreign nationals, collaborative research involving U.S. and foreign participants, and training of U.S. scientists abroad and foreign scientists in the United States.

    Additional legislation (the current Public Health Service Act 3) expanded NCI’s information dissemination activities to include providing information and education programs for patients and the public to help individuals take steps to reduce their risk of cancer, to make them aware of early detection techniques and motivate the appropriate utilization of these techniques, to help individuals deal with cancer if it strikes, and to provide information to improve long-term survival. In addition, NCI was charged with continuing and expanding programs to provide physicians and the public with state-of-the-art information about the treatment of individual types of cancer and to identify clinical trials that might benefit patients while advancing knowledge of cancer treatment.

  7. Where is NCI located?
  8. NCI is located at 9000 Rockville Pike, Bethesda, MD 20892.

  9. What is NCI's annual budget?
  10. In Fiscal Year 2008, the NCI budget was $4.83 billion, most of which was used to fund grants and contracts to universities, medical schools, cancer centers, research laboratories, and private firms in the United States and about 60 other countries around the world. The balance of the funds supported research activities conducted at NCI.

  11. Is progress being made in the fight against cancer?
  12. Because of the work of NCI scientists and cancer researchers throughout the United States and the rest of the world, real progress is being made against cancer. In the United States, the rate of new cancer cases overall has been declining since 1999, and the rate of cancer deaths overall has been decreasing for more than a decade. These trends reflect improvements in cancer treatment and advances in technology that have led to better tools for understanding, detecting, and diagnosing cancer. People with cancer are living longer and have a better quality of life than ever before. In 2008, there were more than 11 million cancer survivors in the United States.

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Glossary Terms

clinical researcher (KLIH-nih-kul reh-SER-cher)
A health professional who works directly with patients, or uses data from patients, to do research on health and disease and to develop new treatments. Clinical researchers may also do research on how health care practices affect health and disease.
epidemiology (EH-pih-dee-mee-AH-loh-jee)
The study of the patterns, causes, and control of disease in groups of people.
palliative care (PA-lee-uh-tiv...)
Care given to improve the quality of life of patients who have a serious or life-threatening disease. The goal of palliative care is to prevent or treat as early as possible the symptoms of a disease, side effects caused by treatment of a disease, and psychological, social, and spiritual problems related to a disease or its treatment. Also called comfort care, supportive care, and symptom management.
quality of life
The overall enjoyment of life. Many clinical trials assess the effects of cancer and its treatment on the quality of life. These studies measure aspects of an individual’s sense of well-being and ability to carry out various activities.
survivorship (ser-VY-ver-ship)
In cancer, survivorship covers the physical, psychosocial, and economic issues of cancer, from diagnosis until the end of life. It focuses on the health and life of a person with cancer beyond the diagnosis and treatment phases. Survivorship includes issues related to the ability to get health care and follow-up treatment, late effects of treatment, second cancers, and quality of life. Family members, friends, and caregivers are also part of the survivorship experience.
translational research (trans-LAY-shuh-nul reh-SERCH)
A term used to describe the process by which the results of research done in the laboratory are used to develop new ways to diagnose and treat disease.


Table of Links

1http://legislative.cancer.gov/history/1937
2http://legislative.cancer.gov/history/phsa/1971
3http://legislative.cancer.gov/history/phsa
4http://www.cancer.gov/cancertopics/factsheet/NCI
5http://www.cancer.gov/newscenter/pressreleases/NCCCPpilotQandA
6http://www.cancer.gov/cancertopics/types/disparities
7http://www.cancer.gov/espanol
8http://obf.cancer.gov/financial/factbook.htm
9http://www.cancer.gov/ncicancerbulletin
10http://www.cancer.gov/nci-international-portfolio