Treatment of recurrent oropharyngeal cancer may include the following:

• Surgery if radiation therapy did not remove all the cancer.
• Radiation therapy (if not previously used) or additional surgery if the first surgery did not remove all the cancer.
• A clinical trial of chemotherapy.
• A clinical trial of hyperthermia therapy with radiation therapy.

Following treatment, it is important to have careful head and neck examinations to look for recurrence. Check-ups will be done monthly in the first year, every 2 months in the second year, every 3 months in the third year, and every 6 months thereafter.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with recurrent oropharyngeal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

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